Krebs voj voog

Krebs voj voog

Txawm hais tias koj tau kawm txog biology hauv tsev kawm ntawv theem siab, lossis tau nyeem txog kev paub txog cov nqaij leeg, koj yeej tau hnov ​​ntawm tus Krebs voj voogCov. Nws yog ib qho ntawm cov theem ntawm theem ntawm cov roj ntsha aerobic respiration uas tshwm sim hauv peb lub cev. Nws tseem paub los ntawm lub npe ntawm lub voj voog ntawm citric acid thiab yog theem ntawm kev zom zaubmov uas tshwm sim hauv mitochondrial matrix ntawm txhua lub tsiaj tsiaj.

Hauv tsab xov xwm no peb yuav qhia koj seb tus yam ntxwv yog dab tsi, kauj ruam los ntawm ntu ntawm ntu ntawm krebs to thiab lawv qhov tseem ceeb ntawm qhov dav.

Theem ntawm cellular ua pa

mitochondria

Ua ntej peb tuaj yeem piav qhia lub krebs lub voj voog yog dab tsi, peb yuav tsum nco ntsoov tias kev ua pa ntawm tes ua haujlwm li cas, vim nws yog qhov tseem ceeb heev. Cia peb pom dab tsi yog theem ntawm kev ua pa ntawm cellular. Nws tshwm sim hauv 3 qib loj:

  • Glycolysis: Qhov no yog txheej txheem uas cov piam thaj tau tawg ua feem me. Thaum lub sijhawm cov txheej txheem no pyruvate lossis pyruvic acid yog tsim uas yuav ua rau Acetyl-CoA.
  • Krebs phaum: Hauv lub voj voog Krebs, Acetyl-CoA yog oxidized rau CO2.
  • Cov pa ntawm txoj sia: Feem ntau ntawm lub zog tsim tawm ntawm no los ntawm kev hloov cov hluav taws xob los ntawm hydrogen. Lub zog no tshwm sim los ntawm kev txiav tawm cov koom nrog hauv txhua kauj ruam dhau los.

Lub voj voog krebs yog dab tsi

krebs kev tawm tsam

Yuav ua li cas lub ntsws ua haujlwm ntawm tes, uas suav nrog hauv ib ntawm cov kauj ruam ntawm lub voj voog no, cia saib seb nws hais txog dab tsi. Peb paub tias nws yog lub voj voog nyuaj thiab nws muaj ntau lub zog uas pab cov metabolism hauv cellular. Yog tias tsis muaj lub voj voog no, txhua lub hlwb tsis tuaj yeem ua tiav cov haujlwm uas tseem ceeb heev rau peb lub cev. Lub hom phiaj kawg ntawm lub voj voog krebs yog los txhawb qhov tawg ntawm qhov kawg ntawm cov khoom lag luam ntawm cov khoom noj carbohydrates, lipids thiab qee cov amino acids.

Thaum peb noj cov zaub mov peb yuav tsum paub tias macronutrients lub ntsiab yog cov khoom noj carbohydrates, cov protein thiab cov rog. Proteins yog, nyeg, ua los ntawm cov amino acids. Vim li no, hauv kev pub mis krebs cov voj voog yog qhov tseem ceeb. Txhua yam khoom uas nkag rau hauv lub cev los ntawm cov khoom noj tau dhau los hauv Acetyl-CoA nrog kev dim pa ntawm CO2 thiab H2O thiab synthesis ntawm ATP.

Ua tsaug rau cov synthesis no, nws yog qhov uas lub zog uas lub hlwb yuav tsum siv thiaj li ua tiav lawv lub zog. Peb muaj ntau yam kev nruab nrab thoob plaws txhua theem ntawm lub voj voog uas lawv siv los ua kev sib txuas ua ntej hauv kev sib txuas ntawm cov amino acids thiab lwm yam biomolecules. Ua tsaug rau lub voj voog no peb tuaj yeem txais lub zog los ntawm cov molecules ntawm organic zaub mov. Lub zog no uas peb tau peb tuaj yeem hloov nws mus rau cov lwg me me rau kev siv hauv kev ua ub no hauv tes thiab peb tuaj yeem ua peb lub luag haujlwm tseem ceeb thiab txhua yam kev ua haujlwm ntawm lub cev niaj hnub los ua

Hauv lub voj voog krebs peb pom qee cov tshuaj lom neeg lawv yog cov feem ntau oxidative nyob rau hauv qhov. Txhua qhov kev xav tau xav tau pa oxygen thiaj li ua tau. Txhua qhov tshuaj lom neeg cov tshuaj lom neeg muaj kev koom tes ntawm qee cov enzymes pom hauv mitochondria ntawm cov hlwb. Txhua tus enzymes muaj lub cim tseem ceeb ntawm kev muaj peev xwm catalyze tshuaj lom neeg tshua. Thaum peb tham txog catalyzing qhov kev tawm tsam peb tab tom hais txog qhov yuav nce tus nqi ntawm cov tshuaj tiv thaiv uas tau hloov pauv mus ua khoom lag luam.

Cov kauj ruam ntawm krebs phaum

tshuaj lom neeg

Muaj cov tshuaj lom neeg ntau lub sijhawm nyob hauv lub voj voog no uas xav kom oxygen xa mus. Thawj qhov tshuaj tiv thaiv yog qhov oxidative decarboxylation ntawm pyruvate. Hauv cov tshuaj tiv thaiv no, cov piam thaj tau los ntawm qhov kev ua tsis tau ntawm do hau yog hloov pauv mus rau ob lwg ntawm pyruvic acid los yog pyruvate. Cov kua nplaum nyob rau hauv Glycolysis hloov zuj zus thiab dhau los ua qhov tseem ceeb ntawm Acetyl-CoA. Qhov oxidative decarboxylation ntawm pyruvate pib nrog lub voj voog ntawm citric acid. Qhov kev tawm tsam tshuaj no sib raug rau kev tshem tawm cov pa roj carbon dioxide thiab pyruvate uas tsim nyob rau hauv cov pab pawg neeg acetyl uas khi rau coenzyme A. Hauv qhov kev tawm tsam tshuaj lom neeg no, NADH tsim tawm los ua lub zog tsim cov roj molecule.

Thaum Acetyl-CoA qauv tsim tau, uas yog thaum lub voj voog kreb yuav siv qhov chaw hauv matrix ntawm mitochondria. Lub hom phiaj ntawm ntu no yog kom los sib sau ua ke ntawm cov xov ntawm lub cev muaj oxidation los oxidize tag nrho cov carbons thiab muaj peev xwm hloov mus rau hauv cov pa roj carbon dioxide. Txhawm rau kom tag nrho cov kev fab tshuaj no tshwm sim, kev muaj pa oxygen yog qhov tsim nyog txhua lub sijhawm. Yog li, Peb tau hais ua ntej pib piav txog lub voj voog krebs qhov tseem ceeb ntawm kev ua pa ntawm tes.

Txhua yam nws pib nrog enzyme citrate synthetase uas pabcuam rau catalyze cov tshuaj lom neeg hauv kev hloov pauv ntawm Acetyl pawg mus rau oxaloacetic acid uas ua rau citric acid ua thiab tso tawm coenzyme A. Lub npe ntawm lub voj voog no cuam tshuam nrog kev tsim ntawm citric acid thiab tag nrho cov tshuaj lom neeg cov tshuaj tshwm sim ntawm no.

Ntxiv oxidation thiab decarboxylation kev tig rov qab tshwm sim hauv cov kauj ruam hauv qab no. Cov kev tsis haum no ua rau ketoglutaric acid tsim. Thaum lub sijhawm ua cov txheej txheem, cov pa roj carbon dioxide raug tso tawm thiab NADH thiab H raug tsim. Cov ketoglutaric acid tau dhau los ntawm oxidative decarboxylation cov tshuaj tiv thaiv uas yog catalyzed nrog qhov enzyme complex uas Acetyl CoA thiab NAD yog ib feem. Tag nrho cov kev cuam tshuam no yuav ua rau succinic acid, NADH, thiab GTP molecule uas yuav hloov nws lub zog mus rau ADP cov qauv tsim tawm ATP.

Cov kauj ruam kawg ntawm lub voj voog no lawv tsuas yog tsom rau qhov tseeb tias succinic acid tuaj yeem oxidized los ua fumaric acidCov. Hom kua qaub no paub los ntawm lub npe fumarate. Nws cov coenzyme yog ADF. Ntawm no FADH2 yog yuav tsum tsim, uas yog lwm lub zog cov roj ntsha molecule. Thaum kawg, fumaric acid tsis kaj siab yuav tsum tau tsim malic acid tseem hu ua malate. Txhawm rau xaus lub voj voog ntawm krebs, Malic acid pib ua rau oxidize rau maj mam tsim oxaloacetic acid. Txoj kev no, lub voj voog rov qab pib dua thiab dua txhua qhov kev cuam tshuam uas peb tau hais tshwm sim dua los ntawm qhov pib.

Kuv vam tias nrog cov ntaub ntawv no koj tuaj yeem kawm paub ntau ntxiv txog lub voj voog krebs thiab nws cov yam ntxwv.


Cov ntsiab lus ntawm tsab xov xwm ua raws li peb cov ntsiab cai ntawm kev tswj hwm kev ncaj nceesCov. Tshaj tawm ib qho yuam kev nyem no.

Yog thawj tus tuaj tawm tswv yim

Tso koj saib

Koj email chaw nyob yuav tsis tsum luam tawm. Yuav tsum tau teb cov cim nrog *

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  1. Lub luag haujlwm rau cov ntaub ntawv: Miguel Ángel Gatón
  2. Lub hom phiaj ntawm cov ntaub ntawv: Tswj SPAM, kev tswj xyuas tawm tswv yim.
  3. Sau raws cai: Koj kev tso cai
  4. Kev sib txuas lus ntawm cov ntaub ntawv: Cov ntaub ntawv yuav tsis raug xa mus rau lwm tus neeg thib peb tsuas yog los ntawm kev txiav txim siab raug cai.
  5. Cov ntaub ntawv khaws cia: Cov Ntaub Ntawv khaws tseg los ntawm Occentus Networks (EU)
  6. Txoj Cai: Txhua lub sijhawm koj tuaj yeem txwv, rov qab thiab tshem tawm koj cov ntaub ntawv.